Shining a FLASHlight on Ultrahigh Dose-Rate Radiation and Possible Late Toxicity | Clinical Cancer Research | American Association for Cancer Research

2022-09-03 10:13:21 By : Ms. Daisy Dai

Amit Maity, Constantinos Koumenis; Shining a FLASHlight on Ultrahigh Dose-Rate Radiation and Possible Late Toxicity. Clin Cancer Res 1 September 2022; 28 (17): 3636–3638. https://doi.org/10.1158/1078-0432.CCR-22-1255

A recent study reported results from a clinical trial in cats and from experiments in mini-pigs in which a single dose of radiotherapy was delivered at ultrahigh dose rates (FLASH). There was acceptable acute toxicity; however, some animals suffered severe late toxicity, raising caution in the design of future trials.

See related article by Rohrer Bley et al., p. 3814

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